Gluconolactone

Gluconolactone is one of skincare's most versatile yet gentle ingredients. If you're looking for an ingredient that can exfoliate, moisturize, and protect your skin all at once - without causing irritation - gluconolactone might be perfect for you. Research shows it's even more effective at hydrating skin than glycerin, a traditional moisturizing ingredient [1].

What makes gluconolactone particularly special is how well it works for all skin types. If you have dry or sensitive skin (Types 1 and 2), research demonstrates it can significantly improve hydration and strengthen your skin's protective barrier [2]. This helps prevent moisture loss and protects against irritants. For those with oily or combination skin (Types 3, 4, and 5), studies show it can help regulate oil production while providing necessary hydration[3]. Most importantly, it doesn't increase sun sensitivity like many other exfoliating ingredients do - in fact, it actually helps protect against UV damage [4]!

For specific skin concerns, gluconolactone has impressive credentials. Clinical studies show it's more effective than benzoyl peroxide for treating acne while causing less irritation [5]. If you're concerned about aging, research demonstrates it can protect against UV damage and may help stimulate collagen production [6]. It's particularly beneficial for sensitive skin conditions like rosacea, where studies show it can help reduce redness and irritation when used alongside other treatments [7].

The science behind gluconolactone shows it's one of the rare skincare ingredients that's both highly effective and extremely gentle. Research indicates it can improve skin hydration, barrier function, and overall appearance without the irritation often associated with other active ingredients [8]. Whether you're dealing with sensitivity, acne, aging concerns, or just want to maintain healthy skin, gluconolactone offers evidence-based benefits that make it worth considering for your skincare routine.

References

1. Technical Data Sheet Manufacturer External (Arxada Ltd, 2023)
2. Berardesca E, et al. 'Alpha hydroxyacids modulate stratum corneum barrier function'. British Journal of Dermatology. 1997;137(6):934-938. DOI: 10.1046/j.1365-2133.1997.19892069.x
3. Jarząbek‐Perz S, et al. 'Evaluation of the effects of 10% and 30% gluconolactone chemical peel on sebum, pH, and TEWL'. Journal of Cosmetic Dermatology. 2023;22:3305-3312. DOI: 10.1111/jocd.15864
4. Bernstein EF, et al. 'The polyhydroxy acid gluconolactone protects against ultraviolet radiation in an in vitro model of cutaneous photoaging'. Dermatologic Surgery. 2004;30(2):189-195. DOI: 10.1111/j.1524-4725.2004.30058.x
5. Hunt MJ, Barnetson RS. 'A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne'. Australasian Journal of Dermatology. 1992;33(3):131-134. DOI: 10.1111/j.1440-0960.1992.tb00103.x
6. Lee KH, et al. 'Cultivation of human skin cells under physiological oxygen concentration modulates expression of skin significant genes and response to hydroxy acids'. Biochemical and Biophysical Research Communications. 2021;551:161-167. DOI: 10.1016/j.bbrc.2021.03.011
7. Draelos ZD, et al. 'An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patients'. Journal of Cosmetic Dermatology. 2006;5(1):23-29. DOI: 10.1111/j.1473-2165.2006.00220.x
8. Kornhauser A, et al. 'Applications of hydroxy acids: classification, mechanisms, and photoactivity'. Clinical, Cosmetic and Investigational Dermatology. 2010;3:135-142. DOI: 10.2147/CCID.S9042